Prior to this incident, Irikah prevented an assassination on an old salarian at a park by placing herself in the targeting laser's way. She wasn't helpless herself as she personally dealt with one attacker. It was then that Thane Krios physically intervened and helped her put down the intruders.
Some parties had "moral objections" to her work, which resulted in thugs breaking in at her lab and attempting to destroy the place. Irikah was a lab researcher working on a vaccine for a rare hanar disease.
“I guess I want to stand for something too.” - Spoilers for Mass Effect: Foundation follow.
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